Collective Synchronous Spiking in a Brain Network of Coupled Nonlinear Oscillators.
Collective Synchronous Spiking in a Brain Network of Coupled Nonlinear Oscillators.
复制标题
耦合非线性振荡器脑网络中的集体同步尖峰。
DOI：
10.1103/physrevlett.126.158102
复制
发表时间：
2021-04-16
影响因子：
8.6
通讯作者：
Frank LR
中科院分区：
文献类型：
--
作者：
Galinsky VL;Frank LR
在人脑中传播的非线性振荡模式（波）的网络被证明产生集体同步尖峰活动（超同步尖峰）时，考虑到模式之间的振幅和相位耦合。参与网络的模式的非线性行为是弱倏逝皮层波的非共振动力学的结果，如最近所示，当通过大脑皮层的非均匀各向异性介质特性传播时，遵守逆频率-波数色散关系。该描述提供了小振幅相位耦合振荡器的网络中的同步的简单化模型与用脉冲或振幅耦合尖峰发放神经元的各种经验拟合模型构建的网络中的同步的简单化模型之间的缺失环节。总的来说，在信中提出的相位-振幅耦合机制显示出更有效的同步相比，目前的标准方法，并证明了出现集体同步尖峰从阈下振荡，无论是相位或振幅耦合单独是无法解释的。
A network of propagating nonlinear oscillatory modes (waves) in the human brain is shown to generate collectively synchronized spiking activity (hypersynchronous spiking) when both amplitude and phase coupling between modes is taken into account. The nonlinear behaviour of the modes participating in the network are the result of the non-resonant dynamics of weakly evanescent cortical waves that, as shown recently, adhere to an inverse frequency-wavenumber dispersion relation when propagating through an inhomogeneous anisotropic media characteristic of the brain cortex. This description provides a missing link between simplistic models of synchronization in networks of small amplitude phase coupled oscillators and in networks built with various empirically fitted models of pulse or amplitude coupled spiking neurons. Overall the phase–amplitude coupling mechanism presented in the Letter shows significantly more efficient synchronization compared to current standard approaches and demonstrates an emergence of collective synchronized spiking from subthreshold oscillations that neither phase nor amplitude coupling alone are capable of explaining.