Semen quality and sexual hormones in greenhouse workers

Semen quality and sexual hormones in greenhouse workers
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DOI:
10.5271/sjweh.573
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发表时间:
2000-12-01
影响因子:
6.3
通讯作者:
Bonde, JP
Bonde, JP
中科院分区:
医学2区
文献类型:
--
作者:
Abell, A;Ernst, E;Bonde, JP

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目的本研究旨在确定接触农药的温室工人的睾丸功能。方法对来自30个观赏花卉温室的199名合格男性中的122名(61%)进行精液检查。根据世界卫生组织指南测量精子浓度、形态和活力,并通过计算机辅助分析视频记录确定曲线精子速度。根据专家对目前从培养物、农药制剂和农药残留从叶子到手的转移中暴露于农药的判断,并根据在温室中工作的年限,形成了三个小组。的风险估计进行了调整的影响,禁欲和其他潜在的混杂factors.Results根据目前的暴露的精子浓度和正常精子的比例的中位数值分别为60%和14%,分别低于高水平暴露组(N=13)比低水平组(N=44),和中间组的值落在两者之间。高水平和低水平暴露组之间的调整差异具有统计学意义,而精子和性激素的活力和速度没有观察到差异。在温室工作超过10年的男性,精子浓度的中位数比在温室工作超过10年的男性低40%。
Objectives This study focused on determining the testicular function of greenhouse workers exposed to pesticides.Methods semen was examined for 122 of 199 eligible men (61%) from 30 ornamental flower greenhouses. Sperm concentration, morphology, and viability were measured according to World Health Organization guidelines, and the curvilinear sperm velocity was determined by a computer-assisted analysis of video recordings. Three groups were formed according to expert judgment of current exposure to pesticides from cultures, pesticide formulations, and the transfer of pesticide residues from leaves to hands, and also ranked according to years of work in a greenhouse. The risk estimates were adjusted for the effects of sexual abstinence and other potentially confounding factors.Results According to current exposure the median values of sperm concentration and the proportion of normal spermatozoa were 60% and 14% lower, respectively, in the high-level exposure group (N=13) than in the low-level group (N=44), and the values of the intermediate group fell in between. The adjusted differences between the high-level and low-level exposure groups were statistically significant, while no differences were observed for the viability and velocity of sperm and sexual hormones. The median sperm concentration was 40% lower for the men with >10 years' experience in a greenhouse than for those with