Flash nanoprecipitation of ultra-small semiconducting polymer dots with size tunability

Flash nanoprecipitation of ultra-small semiconducting polymer dots with size tunability
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具有尺寸可调性的超小半导体聚合物点的闪光纳米沉淀

DOI:
10.1039/c9cc09651e
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发表时间:
2020
影响因子:
4.9
通讯作者:
Wang Lun
Wang Lun
中科院分区:
化学2区
文献类型:
--
作者:
He Yuezhen;Fan Xinyue;Sun Jian;Liu Rui;Fan Zhen;Zhang Zhijie;Chang Xin;Wang Baojuan;Gao Feng;Wang Lun

文献摘要

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小尺寸的半导体聚合物点 (Pdot) 提供更好的组织和亚细胞渗透性,同时最大限度地减少非特异性相互作用,并使 Pdot 通过尿液排泄从人体快速清除。我们采用强大且可扩展的技术,即闪速纳米沉淀,来制备小尺寸的 Pdot(流体动力学直径~10 nm)。
Small-sized semiconducting polymer dots (Pdots) provide better tissue and subcellular penetration while minimizing unspecific interactions, and make the fast clearance of Pdots from human bodies possible by urinary excretion. We employ a powerful and scalable technology, flash nanoprecipitation, to prepare Pdots with small sizes (hydrodynamic diameters ∼10 nm).