Volumetric MRI of the limbic system: anatomic determinants
Volumetric MRI of the limbic system: anatomic determinants
复制标题
DOI：
10.1007/s002340050554
复制
发表时间：
1998-03-01
期刊：
影响因子：
2.8
通讯作者：
Kuzniecky, R
中科院分区：
文献类型：
--
作者：
Bilir, E;Craven, W;Kuzniecky, R
边缘系统包括海马结构、穹窿、乳头体、丘脑和其他整合结构。它涉及包括记忆和情感在内的复杂功能，以及颞叶癫痫等疾病。杏仁核和海马体的体积测量已可靠地用于研究颞叶癫痫患者，但尚未扩展到其他边缘结构。我们对健康个体的海马、杏仁核、穹窿和乳头体进行了体积测量。杏仁核、海马、穹窿和乳头体的体积测量结果显示，左右侧之间有显著性差异（P < 0.001）。除乳头体外，所有结构的测量值的组内变异系数均较高。相同结构的定性图像评估显示半球之间没有不对称性。这种技术可以应用于研究影响边缘系统的疾病。
The limbic system comprises the hippocampal formation, fornix, mamillary bodies, thalamus, and other integrated structures. It is involved in complex functions including memory and emotion and in diseases such as temporal lobe epilepsy. Volume measurements of the amygdala and hippocampus have been used reliably to study patients with temporal lobe epilepsy but have not extended to other limbic structures. We performed volume measurements of hippocampus, amygdala, fornix and mamillary bodies in healthy individuals. Measurements of the amygdala, hippocampus, fornix and mamillary bodies revealed significant differences in volume between right and left sides (P < 0.001). The intraclass coefficient of variation for measurements was high for all structures except the mamillary bodies. Qualitative image assessment of the same structures revealed no asymmetries between the hemispheres. This technique can be applied to the study of disorders affecting the limbic system.