Eremophilanolides and other constituents from the Argentine liverwort Frullania brasiliensis
Eremophilanolides and other constituents from the Argentine liverwort Frullania brasiliensis
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DOI：
10.1016/s0031-9422(01)00452-6
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发表时间：
2002-01-01
期刊：
影响因子：
3.8
通讯作者：
Asakawa, Y
中科院分区：
文献类型：
--
作者：
Bard贸n, A;Mitre, GB;Asakawa, Y
从阿根廷的一种苔类植物Frullania brasiliensis中分离出两种eremophilanolides，5-epidilatanolides A和B，以及一种新的天然联苄，沿着已知的桉烷型倍半萜内酯nepalensolide A、nepalensolide B、（+）-frullanolide和（+）-dihydrofrullanolide、hopanoid zeorin、四种甾醇stigmasta-4，22-dien-3，6-dione、stigmasta-4，22-dien-3-one、豆甾醇和谷甾醇以及痕量的atraric酸。的结构和立体化学的eremophilanolides和联苄基建立了广泛的NMR光谱实验和X-射线晶体学分析相结合。根据圆二色光谱推导了新化合物的绝对构型。(C)2002爱思唯尔科技有限公司版权所有。
Two eremophilanolides, 5-epidilatanolides A and B, as well as a new natural bibenzyl were isolated from an Argentine collection of the liverwort Frullania brasiliensis, along with the known eudesmane-type sesquiterpene lactones nepalensolide A, nepalensolide B, (+)-frullanolide, and (+)-dihydrofrullanolide, the hopanoid zeorin, the four sterols stigmasta-4,22-dien-3,6-dione, stigmasta-4,22-dien-3-one, stigmasterol, and sitosterol, and a trace amount of atraric acid. The structure and stereochemistry of the eremophilanolides and the bibenzyl were established by a combination of extensive NMR spectroscopy experiments and X-ray crystallographic analysis. Absolute configurations of the new compounds were derived on the basis of CD spectra. (C) 2002 Elsevier Science Ltd. All rights reserved.