Shoot meristem maintenance is controlled by a GRAS-gene mediated signal from differentiating cells
Shoot meristem maintenance is controlled by a GRAS-gene mediated signal from differentiating cells
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DOI：
10.1101/gad.230702
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发表时间：
2002-09-01
影响因子：
10.5
通讯作者：
Kuhlemeier, C
中科院分区：
文献类型：
--
作者：
Stuurman, J;J채ggi, F;Kuhlemeier, C
植物茎的发育依赖于茎顶端分生组织（SAM）中一组未分化细胞的永久存在。在矮牵牛突变体毛状分生组织（火腿），芽分生组织分化胚后的延续对着茎。HAM编码GRAS家族的一个假定的转录因子，其从侧向器官原基和茎原细胞的L3衍生组织非细胞自主地起作用。HAM与EQUATOR（PhWUSCHEL）平行作用，并且是对EQUATOR和SHOOTMERISTEMLESS（PhSTM）持续细胞应答所必需的。这揭示了一种新的机制，通过这种机制，来自分化组织的信号可以控制茎尖干细胞的命运。
Plant shoot development depends on the perpetuation of a group of undifferentiated cells in the shoot apical meristem (SAM). In the Petunia mutant hairy meristem (ham), shoot meristems differentiate postembryonically as continuations of the subtending stem. HAM encodes a putative transcription factor of the GRAS family, which acts non-cell-autonomously from L3-derived tissue of lateral organ primordia and stem provasculature. HAM acts in parallel with TERMINATOR (PhWUSCHEL) and is required for continued cellular response to TERMINATOR and SHOOTMERISTEMLESS (PhSTM). This reveals a novel mechanism by which signals from differentiating tissues extrinsically control stem cell fate in the shoot apex.