Lactobacilli, mutants streptococci and dental caries: a longitudinal study in 2-year-old children up to the age of 5 years.
Lactobacilli, mutants streptococci and dental caries: a longitudinal study in 2-year-old children up to the age of 5 years.
复制标题
乳酸杆菌、突变链球菌和龋齿：一项针对 2 岁至 5 岁儿童的纵向研究。
作者：
F. Roeters;J. Van Der Hoeven;R. Burgersdijk;M. Schaeken
对252名学龄前儿童进行了为期3年的队列研究，以早期识别龋齿活跃的个体。在此期间，收集了关于从2岁到5岁获得突变链球菌和乳酸杆菌的信息。在基线时，43%的儿童检测到突变链球菌，而乳酸杆菌的检测频率较低（11.5%）。在个体水平上，在研究期间，牙菌斑和唾液中变形链球菌和乳酸杆菌的菌落形成单位的数量变化很大。母亲唾液中乳酸杆菌和突变链球菌的数量与儿童唾液和牙菌斑的数量之间的相关性很低，从未超过r = 0.22。变异链球菌或乳酸杆菌的数量与糖摄入量之间的相关性也很低（< r = 0.22）。然而，在2.5岁以上的儿童中，临床龋齿评分与唾液中的乳酸杆菌（范围0.31-0.62）和牙菌斑或唾液中的变形链球菌（范围0.24-0.46）之间的相关性非常显著（p < 0.01）。
A 3-year cohort study was carried out in 252 pre-school children for early identification of caries-active individuals. During this period information was collected about the acquisition of mutants streptococci and lactobacilli from the age of 2 till 5 years old. At baseline mutants streptococci were detected in 43% of the children while the detection frequency of lactobacilli was low (11.5%). On an individual level, numbers of colony-forming units of mutans streptococci and lactobacilli in plaque and saliva varied largely during the study period. The correlations between the numbers of lactobacilli and mutants streptococci in the saliva of the mother and the saliva and plaque of the child were low and never exceeded r = 0.22. Very low correlations (< r = 0.22) were also found between the numbers of mutans streptococci or lactobacilli and the diet in terms of the number of sugar intakes. Nevertheless, in children older than 2.5 years correlations between the clinical caries score and lactobacilli in saliva (range 0.31-0.62) and mutans streptococci in plaque or saliva (range 0.24-0.46) were highly significant (p < 0.01).