Whole grain food diet slightly reduces cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis
Whole grain food diet slightly reduces cardiovascular risks in obese/overweight adults: a systematic review and meta-analysis
复制标题
全麦食品饮食略微降低肥胖/超重成年人的心血管风险：系统评价和荟萃分析
DOI：
10.1186/s12872-020-01337-z
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发表时间：
2019-11
期刊：
影响因子：
--
通讯作者：
Lixin Guo
中科院分区：
文献类型：
--
作者：
Weihao Wang;Jianan Li;Xiaoxi Chen;Miao Yu;Qi Pan;Lixin Guo
BackgroundThe effects of whole grain diet on cardiovascular risks in obese and overweight adults is not well established. Our goal was to conduct a systematic review and meta-analysis on the effect of whole grain diet on cardiovascular risks in obese/overweight adults.MethodsPubMed, Embase and Cochrane were systematically scanned for randomized controlled trials (RCTs), and studies were selected based on certain inclusion and exclusion criteria. The primary outcome was the effectiveness of whole grain food consumption in reducing body weight. The secondary outcomes were the effect of whole grain food consumption on cardiovascular disease (CVD) risk factors including plasma low-density lipoprotein cholesterol (LDL-C), insulin resistance index, blood pressure, body mass index (BMI), C-reactive protein (CRP), and waist circumference in obese/overweight adults.ResultsOur results showed that whole grain consumption was associated with lower body weight (mean difference (MD) = − 0.5, 95% confidence intervals (CI) [− 0.74, 0.25], I2= 35%,P< 0.0001) and lower CRP (MD = -0.36, 95% CI [− 0.54, − 0.18], I2= 69%, P < 0.0001), compared with the control group. However, there were no significant differences in LDL-C (MD = -0.08, 95% CI [− 0.16, 0.00], I2= 27%,P= 0.05), waist circumference (MD = -0.12, 95% CI [− 0.92, 0.68], I2= 44%,P= 0.76), systolic blood pressure (MD = -0.11, 95% CI [− 1.55, 1.33], I2= 3%,P= 0.88), diastolic blood pressure (MD = -0.44, 95% CI [− 1.44, 0.57], I2= 15%,P= 0.39), and fasting glucose (MD = -0.05, 95% CI [− 0.12, 0.01], I2= 31%,P= 0.11) between the two groups.ConclusionThis study suggests that whole grain food consumption can slightly reduce body weight and CRP in obese/overweight population.
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影响因子：
3.6
作者：
Corte CD;Alterio A;Nobili V
通讯作者：
Nobili V
影响因子：
5.3
作者：
通讯作者：
--
影响因子：
5.9
作者：
Peacock A;Hutchinson D;Wilson J;McCormack C;Bruno R;Olsson CA;Allsop S;Elliott E;Burns L;Mattick RP
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Mattick RP
影响因子：
5.9
作者：
Li L;Lietz G;Bal W;Watson A;Morfey B;Seal C
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Seal C
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3.7
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Lankinen M;Kolehmainen M;Jääskeläinen T;Paananen J;Joukamo L;Kangas AJ;Soininen P;Poutanen K;Mykkänen H;Gylling H;Orešič M;Jauhiainen M;Ala-Korpela M;Uusitupa M;Schwab U
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Schwab U