Neural correlates of semantic activation spreading on the path to picture naming in adults who stutter.
Neural correlates of semantic activation spreading on the path to picture naming in adults who stutter.
复制标题
语义激活的神经关联在口吃成年人的图片命名路径上传播。
DOI：
10.1016/j.clinph.2010.03.026
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发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Hinckley,JacquelineJ
中科院分区：
文献类型：
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作者：
Maxfield,NathanD;Huffman,JessicaL;Frisch,StefanA;Hinckley,JacquelineJ
目的 在图像命名的过程中，与图像对象语义相关的单词在心理词典中被激活。我们使用神经科学方法来研究口吃成年人 (AWS) 中的语义激活传播过程。 方法 14 名 AWS 和 14 名不口吃的成年人 (AWNS) 完成了图画词启动任务。在每次试验中，都会延迟命名一张图片。在一些试验中，在命名开始之前，在图片之后出现无人看管的听觉探测词。使用空间-时间主成分分析比较记录的事件相关电位，以探测与图片标签语义相关的单词，以及探测与图片标签语义相关和语音无关的单词。结果在 AWNS 中，语义相关探针与不相关探针的后 N400 幅度减弱，而在 AWS 中，后 N400 幅度增强 语义相关探针与不相关探针。其他 ERP 组件的形态虽然可能相关，但也观察到了边际差异。 结论 N400 后验结果表明，AWS 命名路径上的语义激活传播具有战略性的抑制性影响。其他 ERP 组件幅度的组差异初步表明，AWS 在任务期间分配注意力资源的方式与 AWNS 不同。还讨论了 AWS 中完整概念（相对于词汇语义）启动的初步 ERP 证据。意义这项研究有助于越来越多的描述 AWS 中语言表现的研究。
OBJECTIVEOn the path to picture naming, words that relate semantically to the pictured object become activated in the mental lexicon. We used a neuroscientific approach to investigate this semantic activation spreading process in adults who stutter (AWS).METHODSFourteen AWS and 14 adults who do not stutter (AWNS) completed a picture–word priming task. On each trial, a picture was named at a delay. On some trials, an unattended auditory probe word was presented after the picture, before naming commenced. Event-related potentials recorded to probe words Semantically-Related to the picture labels, and to probe words Semantically- and Phonologically-Unrelated to the picture labels, were compared using spatial–temporal principal component analysis.RESULTSPosterior N400 amplitude was attenuated for Semantically-Related versus Unrelated probes in AWNS, while in AWS posterior N400 amplitude was enhanced for Semantically-Related versus Unrelated probes. Marginal albeit potentially relevant group differences in the morphology of other ERP components were also observed.CONCLUSIONSThe posterior N400 results point to a strategic, inhibitory influence on semantic activation spreading in AWS on the path to naming. Group differences in the amplitude of other ERP components tentatively suggest that AWS allocated attentional resources differently than the AWNS during the task. Preliminary ERP evidence of intact conceptual (as opposed to lexical-semantic) priming in the AWS is also discussed.SIGNIFICANCEThis study contributes to a growing body of research describing linguistic performance in AWS.