RADIATION MANAGEMENT OF BILATERAL RETINOBLASTOMA - THE NEED TO PRESERVE VISION
RADIATION MANAGEMENT OF BILATERAL RETINOBLASTOMA - THE NEED TO PRESERVE VISION
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DOI：
10.1016/0360-3016(80)90221-7
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发表时间：
1980-01-01
影响因子：
7
通讯作者：
STEVENS, KR
中科院分区：
文献类型：
--
作者：
GAGNON, JD;WARE, CM;STEVENS, KR
1944 年至 1978 年间，俄勒冈大学健康科学中心（美国俄勒冈州波特兰）放射治疗科收治了 34 名视网膜母细胞瘤患者（儿童）。这些患者中，25 名患有双侧疾病。大多数患者接受兆伏设备治疗，并在 5 周内接受 5000 拉德的剂量。根据寿命表法，5年生存率为67.6%；如果排除使用正压设备治疗的患者，这一比例将增加至 85.7%。在可评估的患者中，71% 在 5 岁时具有有用的视力；另外 2 名患者在放射治疗后 2 年内仍保持有用视力。讨论了在感觉运动和心理发展的关键时期即使视力有限的价值。正电压设备不应用于照射视网膜母细胞瘤患者。
Thirty-four patients [children] with retinoblastoma were treated in the Radiation Therapy Department of the University of Oregon Health Sciences Center [Portland, Oregon, USA] from 1944 to 1978. Of these patients, 25 had bilateral disease. Most patients were treated with megavoltage equipment and received doses of 5000 rad in 5 wk. According to the lifetable method, 5 yr surival was 67.6%; it increased to 85.7% if patients who were treated with orthovoltage equipment were excluded. Of evaluable patients, 71% had useful vision at 5 yr; an additional 2 patients had useful vision for 2 yr after radiation therapy. The value of even limited vision during this critical time of sensorimotor and psychological development is discussed. Orthovoltage equipment should not be used to irradiate patients with retinoblastoma.