Cross-sectional association between physical strength, obesity, periodontitis and number of teeth in a general population
Cross-sectional association between physical strength, obesity, periodontitis and number of teeth in a general population
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DOI：
10.1111/jcpe.12531
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发表时间：
2016-05-01
影响因子：
6.7
通讯作者：
Meisel, Peter
中科院分区：
文献类型：
--
作者：
Eremenko, Michael;Pink, Christiane;Meisel, Peter
目的：在整个生命过程中，随着年龄的增长，肌肉力量下降，牙床萎缩。握力作为身体健康指标与牙周炎和牙齿数之间可能存在关联。材料和方法：对2089名波美拉尼亚健康研究(SHIP-2)的参与者进行了握力(GS)、人体测量、临床附着丧失、牙齿数量、C反应蛋白和糖化血红蛋白的评估。结果：在调整年龄的多元回归中，体重指数(BMI)和腰臀比(WHR)每减少一mm的牙周附着分别使男性和女性的GS减少1.47 kg(95%CI-2.29~-0.65)和0.38 kg(-0.89~0.14)。相应地，每增加一颗剩余牙齿与更高的GS显著相关。使用相对于体重指数的握力作为结果，这些关系变得更加明显。肥胖指标如BMI和WHR与GS和牙周炎相关，调节GS与牙周炎的关系，但不同性别之间的影响不同。结论：牙周炎与GS有关，主要是通过与肥胖和炎症相关的人体测量学指标进行修正。推测的机制包括随着年龄的增长而下降的因素的相互作用。
Aim: Muscle strength declines and gums recede with increasing age across the life course. Possible associations exist between handgrip strength as an indicator of physical fitness and periodontitis and number of teeth.Material and Methods: Handgrip strength (GS), anthropometric measures, clinical attachment loss, number of teeth, C-reactive protein and glycated haemoglobin were assessed in 2089 participants of the Study of Health in Pomerania (SHIP-2). Linear regression including interaction with age was used to estimate the association between clinical attachment level, number of teeth and GS.Results: In multiple regression adjusted for age, body mass index (BMI) and waist-to-hip ratio (WHR) each mm of diminished periodontal attachment was associated with reduction in GS by 1.47kg (95% CI -2.29 to -0.65) and 0.38kg (-0.89 to 0.14) in men and women respectively. Correspondingly, each additional remaining tooth was significantly associated with higher GS. Using handgrip strength relative to BMI as outcome, these relationships become even more apparent. Indicators of obesity such as BMI and WHR associated with both GS and periodontitis modulate the relationship between GS and periodontitis with a different impact between the sexes.Conclusion: Periodontitis is associated with GS modified mainly by anthropometric measures related to adiposity and inflammation. Putative mechanisms encompass interactions of factors declining with increasing age.