A phytotoxic pimarane diterpene of Sphaeropsis sapinea f sp cupressi, the pathogen of a canker disease of cypress
A phytotoxic pimarane diterpene of Sphaeropsis sapinea f sp cupressi, the pathogen of a canker disease of cypress
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DOI：
10.1016/0031-9422(96)00206-3
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发表时间：
1996-08-01
期刊：
影响因子：
3.8
通讯作者：
Frisullo, S
中科院分区：
文献类型：
--
作者：
Evidente, A;Sparapano, L;Frisullo, S
一种名为Sphaeropsidin A的植物毒性代谢产物是由Sphaeropsis saponif. Cupressi，一种引起意大利柏树（Cupressus sempervirens）溃疡病的真菌。光谱数据表明，sphaeropsidin A是相同的海松烷二萜类抗生素先前分离出的一些曲霉属。当被三种柏木的嫩枝和两种草本植物的插条吸收时，0.1mg/ml的球壳菌素A分别引起叶片黄化、布朗宁、枯死和黄化、坏死和上性。将0.1 mg/ml（-1）球胞苷A溶液皮下注射到幼年柏树中，导致皮质组织出现纵向裂缝和深棕色变色。该化合物显示抗微生物活性对12种真菌物种时，测定浓度范围从10至100 μ g ml（-1）。这是首次报道sphaeropsidin A是一种非选择性真菌毒素。
A phytotoxic metabolite, named sphaeropsidin A, is produced in vitro by Sphaeropsis sapinea f. sp. cupressi, a fungus that causes a canker disease of Italian cypress (Cupressus sempervirens). The spectroscopic data indicates that sphaeropsidin A is identical with a pimarane diterpenoid antibiotic previously isolated from some Aspergillus spp. When absorbed by severed twigs of three species of Cupressus and cuttings of two herbaceous plants, sphaeropsidin A at 0.1 mg ml(-1) produced leaf yellowing, browning and dieback and yellowing of leaf, necrosis and epinasty, respectively. Subperidermal injection of a 0.1 mg ml(-1) solution of sphaeropsidin A into young cypress trees caused longitudinal fissures and dark brown discolouration of cortical tissues. The compound showed antimicrobial activity towards 12 fungal species when assayed at a concentration range from 10 to 100 mu g ml(-1). This is the first report showing that sphaeropsidin A is a non-selective fungal phytotoxin.