Guiding Principles for the Conduct of Observational Critical Care Research for Coronavirus Disease 2019 Pandemics and Beyond: The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study Registry.
Guiding Principles for the Conduct of Observational Critical Care Research for Coronavirus Disease 2019 Pandemics and Beyond: The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study Registry.
复制标题
DOI：
10.1097/ccm.0000000000004572
复制
发表时间：
2020-11
影响因子：
8.8
通讯作者：
Gajic O
中科院分区：
文献类型：
--
作者：
Walkey AJ;Sheldrick RC;Kashyap R;Kumar VK;Boman K;Bolesta S;Zampieri FG;Bansal V;Harhay MO;Gajic O
在大流行期间利用观测数据为患者的反应和护理提供信息面临着独特的挑战。危重病医学会发现病毒感染和呼吸系统疾病通用研究COVID 2019注册中心核心数据和研究方法团队在整个2020年3月至6月期间通过虚拟会议召开会议，以确定开发大流行疾病注册中心的最佳实践目标，以支持快速数据收集和分析。国际，多中心住院病人登记。没有。没有。大规模观察性数据收集需要：1)质量保证和许多站点的协调一致；2)从许多潜在的研究问题中进行选择的透明过程；3)在设计描述性、预测性和推断性研究时使用最佳做法；(4)在不断更新的数据背景下采用创新的方法来表征随机错误；(5)快速同行审查和报告；以及(6)从注重发现到实施的转变。在此，我们描述了最佳实践的指导原则和创新的建议，以在冠状病毒病2019年病毒感染和呼吸系统疾病全球研究大流行登记中进行研究设计和报告。重症护理学会医学发现病毒感染和呼吸系统疾病2019年世界研究冠状病毒疾病登记寻求制定和实施预先指定的最佳做法，并结合世界各地临床站点的基层努力，以发展临床有用的知识，以应对大流行。
Use of observational data to inform the response and care of patients during a pandemic faces unique challenges. The Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study COVID 2019 Registry Core data and research methodology team convened over virtual meetings throughout March to June 2020 to determine best practice goals for development of a pandemic disease registry to support rapid data collection and analysis. International, multi-center registry of hospitalized patients. None. None. Large-scale observational data collection requires: 1) quality assurance and harmonization across many sites; 2) a transparent process for selecting from among many potential research questions; 3) the use of best practices in design of descriptive, predictive, and inferential studies; (4) innovative approaches to characterize random error in the setting of constantly updated data; (5) rapid peer-review and reporting; and (6) transitions from a focus on discovery to implementation. Herein, we describe the guiding principles to best practices and suggestions for innovations to study design and reporting within the coronavirus disease 2019 Viral Infection and Respiratory Illness Universal Study pandemic registry. Society of Critical Care Medicine Discovery Viral Infection and Respiratory Illness Universal Study coronavirus disease 2019 registry sought to develop and implement prespecified best practices combined with grassroots efforts from clinical sites worldwide in order to develop clinically useful knowledge in response to a pandemic.