Heritability of lateralization in fish: concordance of right-left asymmetry between parents and offspring
Heritability of lateralization in fish: concordance of right-left asymmetry between parents and offspring
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DOI：
10.1016/s0028-3932(00)00018-x
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发表时间：
2000-01-01
期刊：
影响因子：
2.6
通讯作者：
Vallortigara, G
中科院分区：
文献类型：
--
作者：
Bisazza, A;Facchin, L;Vallortigara, G
poeciliid鱼Girardinus falcatus显示出一致的人口偏见，绕道的垂直酒吧障碍优先向左接近一个虚拟的捕食者时，检查它的不对称性似乎是由于优先使用的右眼的侧场固定的生物相关的刺激，如捕食者。为了解开这种横向偏差的起源，我们利用自然群体中存在的个体变异性进行人工选择实验。在迂回测试中得分相似的雄性和雌性交配在一起，并在相同的任务中测试它们的后代。结果表明，父母与子女之间的不对称性在强度和方向上具有显著的相似性。相关性极显著，遗传力估计值大于0.5。这是第一次证明了灵长目动物以外的行为不对称方向的遗传性。这一发现铺平了道路，使用一种新的和合适的动物模型的神经遗传学的偏侧化和可能的识别同源和/或类似的基因之间的脊椎动物大脑不对称。(C)2000爱思唯尔科技有限公司版权所有。
The poeciliid fish Girardinus falcatus shows a consistent population bias to detour a vertical-bar barrier preferentially leftwise when approaching a dummy predator to inspect it; the asymmetry seems to be due to a preferential use of the lateral field of the right eye during fixation of biologically relevant stimuli such as a predator. In order to unravel the origins of this lateral bias, we took advantage of the individual variability present in the natural population to perform artificial selection experiments. Males and females that scored similarly at the detour test were mated together and their progeny were tested in the same task. Results showed that there was a striking similarity in the strength and in the direction of the asymmetries between parents and offspring. Correlation was highly significant and the estimate of heritability was greater than 0.5. This represents the first demonstration of heritability of the direction of a behavioural asymmetry outside the primate order. The finding paves the way to the use of a novel and suitable animal model for the neuro-genetics of lateralization and to the possible identification of homologous and/or analogous genes underlying brain asymmetry among vertebrates. (C) 2000 Elsevier Science Ltd. All rights reserved.