THE EFFECT OF HYPOPHYSECTOMY ON ARTERIAL BLOOD PRESSURE OF DOGS WITH EXPERIMENTAL HYPERTENSION

THE EFFECT OF HYPOPHYSECTOMY ON ARTERIAL BLOOD PRESSURE OF DOGS WITH EXPERIMENTAL HYPERTENSION
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垂体切除术对实验性高血压犬动脉血压的影响

DOI:
10.1152/ajplegacy.1937.120.2.238
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发表时间:
1937
影响因子:
--
通讯作者:
J. E. Sweet
J. E. Sweet
中科院分区:
--
文献类型:
--
作者:
I. Page;J. E. Sweet

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方法。成年的公狗和母狗都被雇佣了。同一研究人员每天在温暖的房间(80华氏度)测量动脉血压。使用Van Leersum(3)的方法,包括确定搏动通过由橡胶压力袖带压迫的颈动脉环的压力。在许多情况下,血压也是通过听诊后腿的动脉来测量的。动脉被挤压了5厘米。宽阔的橡胶袖口缠绕在脚踝上方的腿上。用这种方法可以同时测定收缩压和舒张压。这两种方法在我们手中的范围内是一致的。测量血压,直到我们确定正常的变化是已知的。在盆巴比妥钠麻醉下,按Goldblatt、Lynch、Hanzal和Summerville(1)的方法对右肾动脉行可调银夹。如果血压显著升高,并持续稳定升高30天
METHOD. Both male and female dogs of adult ages were employed. Arterial blood pressure was measured daily by the same investigator in a warm room (80 F.). The method of Van Leersum (3) was used, which consists in ascertaining the pressure at which beats come through a loop of carotid artery compressed by a rubber pressure cuff. In a number of instances, blood pressures were also measured by auscultation over an artery of the hind leg. The artery was compressed by a 5 cm. wide rubber cuff wrapped around the leg just above the ankle joint. By this method both systolic and diastolic pressures could be determined. The two methods agree within close limits in our hands. Blood pressure measurements were made until we felt certain that the normal variations were known. Under pento-barbital anesthesia, an adjustable silver clamp was applied t, o the right renal artery according to the method of Goldblatt, Lynch, Hanzal and Summerville (1). If the blood pressure rose markedly and remained steadily elevated for 30 days