Osteopetrosis, femoral fracture, and chronic osteomyelitis caused by Staphylococcus aureus small colony variants (SCV) treated by girdlestone resection -: 6-year follow-up
Osteopetrosis, femoral fracture, and chronic osteomyelitis caused by Staphylococcus aureus small colony variants (SCV) treated by girdlestone resection -: 6-year follow-up
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DOI：
10.1007/s00402-002-0435-2
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发表时间：
2002-12-01
影响因子：
2.3
通讯作者：
Bettin, D
中科院分区：
文献类型：
--
作者：
Rolauffs, B;Bernhardt, TM;Bettin, D
由金黄色葡萄球菌小菌落变异体引起的慢性骨髓炎与骨硬化症相结合是一种独特的疾病组合，使我们面临重大挑战。治疗方法包括4次连续清创和抗菌治疗。积极的治疗导致脆性和坚硬的骨硬化骨不稳定，11周后，发生股骨颈骨折。进行了股骨挽救手术，在该干预期间获得的培养物保持阴性。在6年的随访中，girdlestone情况仍然显示出可接受的功能结局，没有任何骨髓炎复发。
Chronic osteomyelitis caused by Staphylococcus aureus small colony variants in combination with osteopetrosis is a unique combination of disorders that confronted us with major challenges. The therapeutic approach included four serial debridements and antimicrobial therapy. The aggressive treatment led to an instability of the brittle and hard osteopetrotic bone, and after 11 weeks, a fracture of the femoral neck occurred. A salvage procedure of the femur was performed, and the cultures obtained during this intervention remained negative. At a 6-year follow-up, the girdlestone situation still showed an acceptable functional outcome without any recurrence of osteomyelitis.