One-pot reaction cascades using star polymers with core-confined catalysts
One-pot reaction cascades using star polymers with core-confined catalysts
复制标题
DOI：
10.1002/anie.200502095
复制
发表时间：
2005-01-01
影响因子：
16.6
通讯作者：
Fréchet, JMJ
中科院分区：
文献类型：
--
作者：
Helms, B;Guillaudeu, SJ;Fréchet, JMJ
我的星星！容易制备在其空间受限的核（参见示意图）处含有其它不相容的酸或碱催化剂（例如对甲苯磺酸或4-（二烷基氨基）吡啶部分）的星星聚合物。使用这些星星聚合物的均相催化可以在同一罐中进行反应级联，并且用酸催化的脱保护和亲核胺催化的Baylis-Hillman反应来证明。（图为）
My stars! Star polymers that contain otherwise incompatible acid or base catalysts, such as para-toluenesulfonic acid or 4-(dialkylamino) pyridines moieties, at their sterically restricted cores (see scheme) are readily prepared. Homogeneous catalysis using these star polymers can perform reaction cascades in the same pot and is demonstrated with an acid-catalyzed deprotection and the nucleophilic amine-catalyzed Baylis-Hillman reaction.(Figure Presented)