GIPR Gene Polymorphism and Weight Gain in Patients With Schizophrenia Treated With Olanzapine

GIPR Gene Polymorphism and Weight Gain in Patients With Schizophrenia Treated With Olanzapine
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DOI:
10.1176/appi.neuropsych.13120389
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发表时间:
2015-03-01
影响因子:
2.9
通讯作者:
Someya, Toshiyuki
Someya, Toshiyuki
中科院分区:
医学4区
文献类型:
--
作者:
Ono, Shin;Suzuki, Yutaro;Someya, Toshiyuki

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研究了奥氮平治疗的精神分裂症中胃抑制性多肽受体多态性 rs10423928 与体重指数之间的关联。 A/T+A/A 基因型的体重指数变化显着高于 T/T 基因型。 rs10423928 可以预测精神分裂症患者的体重增加。
Association between gastric inhibitory polypeptide receptor polymorphism, rs10423928, and body mass index in olanzapine-treated schizophrenia was examined. Body mass index change for the A/ T+A/A genotypes was significantly higher than that for the T/T genotype. rs10423928 may predict weight gain in schizophrenia.