Determination of left ventricular wall thickness by angiocardiography.
Determination of left ventricular wall thickness by angiocardiography.
复制标题
通过心血管造影测定左心室壁厚度。
DOI：
10.1016/0002-8703(69)90486-4
复制
发表时间：
1969
影响因子：
4.8
通讯作者：
Elizabeth Hull
中科院分区：
文献类型：
--
作者：
P. Hugenholtz;P. Hugenholtz;E. Kaplan;E. Kaplan;Elizabeth Hull;Elizabeth Hull
用各种方法和不同种类测量从舒张期到收缩期左室壁厚度的变化，表明存在不可接受的差异(范围为15%至100%)。随着心血管造影术方法在人类心脏病研究中被越来越多地接受，对31例有和没有高血压的典型心脏疾病患者进行了这种类型的室壁厚度测量的准确性的研究。舒张末期肌块被认为是最准确的，其体积被认为在收缩过程中不会改变。31名患者中有10名患者的室壁厚度预测值与观察值比较显示完全一致。平均壁厚增加39.8%。这一结果与Mitchell等人报道的在犬身上植入的不透射线标记可以在收缩期间准确测量室壁厚度的结果完全一致。在其余21名患者中，有10名患者随后可以在仔细重新检查胶片时识别预测的室壁厚度。在其余的患者中，无法辨认出真正的左室壁，室壁厚度平均增加了92.5%。其他人也报道了类似的数字。3，13得出结论，直接测量弹射第二阶段(200毫秒之后)的壁厚。收缩开始后)会导致很大的误差，特别是在肥厚的患者。作为对这一问题解的第一次近似，描述了一种计算方法，该方法在前200毫秒内所有情况下的观测值和预测值都完全一致。在宫缩开始后。
Measurements of the change in left ventricular wall thickness from diastole to systole, by a variety of methods and in different species, indicate unacceptable discrepancies (range 15 to 100 per cent). Since angiocardiographic methods are accepted more and more in the study of human heart disease, the accuracy of this type of wall thickness measurement was investigated in 31 patients with representative examples of a variety of cardiac disorders with and without hypertrophy.A method was developed permitting the prediction of wall thickness on any film taken during the cardiac cycle. End-diastolic muscle mass was considered the most accurate and its volume was assumed not to change during systole. Comparison of predicted and observed values for wall thickness showed complete agreement in 10 of the 31 patients. Average wall thickness increased 39.8 per cent. This result is in complete agreement with those reproted by Mitchell and associates5in dogs in whom implanted radiopaque markers permitted accurate measurement of wall thickness during systole.In 10 of the remaining 21 patients the predicted wall thickness could subsequently be recognized during a careful re-examination of the films. In the remainder, there was no way in which the true left ventricular wall could be recognized and wall thickness increased an average of 92.5 per cent. Similar figures have been reported by others.3,13It is concluded, that direct measurement of wall thickness during the second phase of ejection (after 200 msec. after onset of contraction) will lead to large errors, particularly in patients with hypertrophy. As a first approximation to a solution for this problem, a computational method is described, which showed complete agreement between observed and predicted values in all cases during the first 200 msec. after the onset of contraction.