Evoked Haptic Sensation in the Hand With Concurrent Non-Invasive Nerve Stimulation
Evoked Haptic Sensation in the Hand With Concurrent Non-Invasive Nerve Stimulation
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DOI：
10.1109/tbme.2019.2895575
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发表时间：
2019-01
影响因子：
4.6
通讯作者：
Luis Vargas;G. Whitehouse;H. Huang;Yong Zhu;Xiaogang Hu
中科院分区：
文献类型：
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作者：
Luis Vargas;G. Whitehouse;H. Huang;Yong Zhu;Xiaogang Hu
目的：触觉是假手使用者直观控制假手的关键。在这项研究中，我们试图使用经皮神经刺激来评估通过多个渠道同时刺激列车所诱发的触觉知觉。方法：采用2×8电极网向上臂正中神经和尺神经输送电流。首先选择不同的电极来激活感觉轴突，这些轴突可以在手的不同位置产生感觉。然后将电荷平衡的双极刺激同时给予两组具有相位延迟的电极(双重刺激)，以确定诱发的感觉是否可以由沿电极网格的不同位置分别给予的单一刺激(单一刺激)的感觉构建。改变了两个刺激序列之间的时间延迟，以评估潜在的干扰。还评估了测试过程中触觉的短期稳定性。结果：双刺激时的诱发感觉主要是单次刺激感觉的直接总和。两个刺激位置之间的延迟对诱发感觉的影响很小，在一次测试中重复测试也是稳定的。结论：我们的结果表明，通过直接组合多个刺激序列的反应，可以构建手部不同区域的触觉。刺激之间的干扰很小。意义：当假体与不同物体相互作用时，结果将允许我们构建特定的触觉模式，这可能有助于改善假体的用户体验。
Objective: Haptic perception is critical for prosthetic users to control their prosthetic hand intuitively. In this study, we seek to evaluate the haptic perception evoked from concurrent stimulation trains through multiple channels using transcutaneous nerve stimulation. Methods: A 2 × 8 electrode grid was used to deliver current to the median and ulnar nerves in the upper arm. Different electrodes were first selected to activate the sensory axons, which can elicit sensations at different locations of the hand. Charge-balanced bipolar stimulation was then delivered to two sets of electrodes concurrently with a phase delay (dual stimulation) to determine whether the evoked sensation can be constructed from sensations of single stimulation delivered separately at different locations (single stimulation) along the electrode grid. The temporal delay between the two stimulation trains was altered to evaluate potential interference. The short-term stability of the haptic sensation within a testing session was also evaluated. Results: The evoked sensation during dual stimulation was largely a direct summation of the sensation from single stimulations. The delay between the two stimulation locations had minimal effect on the evoked sensations, which was also stable over repeated testing within a session. Conclusion: Our results indicated that the haptic sensations at different regions of the hand can be constructed by combining the response from multiple stimulation trains directly. The interference between stimulations were minimal. Significance: The outcomes will allow us to construct specific haptic sensation patterns when the prosthesis interacts with different objects, which may help improve user embodiment of the prosthesis.