A comparative genomics approach revealed evolutionary dynamics of microsatellite imperfection and conservation in genus Gossypium.
A comparative genomics approach revealed evolutionary dynamics of microsatellite imperfection and conservation in genus Gossypium.
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比较基因组学方法揭示了棉属微卫星缺陷和保护的进化动力学
DOI：
10.1186/s41065-017-0034-4
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发表时间：
2017
期刊：
影响因子：
2.7
通讯作者：
Lin Z
中科院分区：
文献类型：
--
作者：
Ahmed MM;Shen C;Khan AQ;Wahid MA;Shaban M;Lin Z
细胞中的分子过程可以靶向微卫星，这是由于长度变化和基序不完美的原因。
检查了各种原始植物物种的基因组序列，以了解整个基因组的基序不完美模式，并且在重复密度，不完美和微片状的长度之间使用各种分析工具，此外，比较基因组学方法在探索gossyp Imperif in Imperif in Comporif in Compotif in Cometift in Compotif中。 13个基因组之间的微卫星的不完善。
结果可能是通过棉质基因组中特异性特异性特征的进化来探索简单非编码遗传元件的比较进化足迹的指令。
本文的在线版本（DOI：10.1186/S41065-017-0034-4）包含补充材料，可供授权用户使用。
Ongoing molecular processes in a cell could target microsatellites, a kind of repetitive DNA, owing to length variations and motif imperfection. Mutational mechanisms underlying such kind of genetic variations have been extensively investigated in diverse organisms. However, obscure impact of ploidization, an evolutionary process of genome content duplication prevails mostly in plants, on non-coding DNA is poorly understood. Genome sequences of diversely originated plant species were examined for genome-wide motif imperfection pattern, and various analytical tools were employed to canvass characteristic relationships among repeat density, imperfection and length of microsatellites. Moreover, comparative genomics approach aided in exploration of microsatellites conservation footprints in Gossypium evolution. Based on our results, motif imperfection in repeat length was found intricately related to genomic abundance of imperfect microsatellites among 13 genomes. Microsatellite decay estimation depicted slower decay of long motif repeats which led to predominant abundance of 5-nt repeat motif in Gossypium species. Short motif repeats exhibited rapid decay through the evolution of Gossypium lineage ensuing drastic decrease of 2-nt repeats, of which, “AT” motif type dilapidated in cultivated tetraploids of cotton. The outcome could be a directive to explore comparative evolutionary footprints of simple non-coding genetic elements i.e., repeat elements, through the evolution of genus-specific characteristics in cotton genomes. The online version of this article (doi:10.1186/s41065-017-0034-4) contains supplementary material, which is available to authorized users.