Axon growth and guidance
Axon growth and guidance
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轴突生长和引导
DOI：
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发表时间：
2007
期刊：
影响因子：
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通讯作者：
D. Bagnard
中科院分区：
文献类型：
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作者：
D. Bagnard
十三、前言……七1。轴突生长的分子机制…1 Celine Bouquet和Fatiha Nothias介绍神经元生长锥及其细胞骨架组织…1轴突伸长机制…细胞外线索对细胞骨架的调控，rho - gtpase的作用…7再生轴突生长锥…10 2。神经网络及其受体……17 Simon W. Moore, Marc Tessier-Lavigne, Timothy E. Kennedy引言网络结构神经网络在神经系统发育中的功能作用网络信号转导成人神经系统中的神经碱…结论与观点……26日3。Eph受体和ephrin配体在轴突引导中的作用。32 . Michael Reber， Robert Hindges和Greg Lemke分子结构……32信号转导机制…34神经系统发育的功能意义……结论与观点……44 4。信号蛋白在轴突生长和引导中的作用…Eric Koncina, Lise Roth， Bertand Gonthier和Dominique Bagnard引言信号蛋白在轴突引导中的功能作用分泌信号素受体：神经肽…跨膜信号蛋白受体的研究进展[j]其他与信号素信号相关的受体…54细胞内信号转导结论……14 .内容：裂缝和它们的受体……65年阿兰
CONTENT Contents xiii PREFACE ... vii 1. MOLECULAR MECHANISMS OF AXONAL GROWTH ... 1 Celine Bouquet and Fatiha Nothias Introduction ...1 The Neuronal Growth Cone and its Cytoskeletal Organization ... 1 Mechanisms of Axonal Elongation ... 6 Regulation of the Cytoskeleton by Extracellular Cues, Role of Rho-GTPases ... 7 Growth Cone of Regenerating Axons ... 10 2. NETRINS AND THEIR RECEPTORS... 17 Simon W. Moore, Marc Tessier-Lavigne and Timothy E. Kennedy Introduction ...17 Netrin Structure ...19 Functional Roles for Netrins during Nervous System Development ...21 Netrin Signal Transduction...22 Netrin in the Adult Nervous System ... 25 Conclusion and Perspectives ...26 3. EPH RECEPTORS AND EPHRIN LIGANDS IN AXON GUIDANCE... 32 Michael Reber, Robert Hindges and Greg Lemke Introduction ...32 Molecular Structure ... 32 Mechanisms of Signal Transduction ... 34 Functional Implication during Nervous System Development ... 39 Conclusion and Perspectives ...44 4. ROLE OF SEMAPHORINS DURING AXON GROWTH AND GUIDANCE ... 50 Eric Koncina, Lise Roth, Bertand Gonthier and Dominique Bagnard Introduction ...50 Functional Roles of Semaphorins during Axon Guidance ... 50 Receptors of Secreted-Semaphorins: The Neuropilins ... 52 Receptors of Transmembrane-Semaphorins: The Plexin Family ...53 Other Receptors Associated with Semaphorin Signaling ... 54 Intracellular Signal Transduction ...56 Conclusion ... 59 xiv Contents 5. SLITS AND THEIR RECEPTORS ... 65 Alain