GAMMA GLOBULIN ANTIGENIC TYPES DEFINED BY HEAVY CHAIN DETERMINANTS

GAMMA GLOBULIN ANTIGENIC TYPES DEFINED BY HEAVY CHAIN DETERMINANTS
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DOI:
10.1126/science.145.3628.168
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发表时间:
1964-01-01
期刊:
影响因子:
56.9
通讯作者:
TOMINAGA, K
TOMINAGA, K
中科院分区:
综合性期刊1区
文献类型:
--
作者:
BALLIEUX, RE;PUTNAM, FW;TOMINAGA, K

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Two populations of immunologically distinguishable 7S gamma globulins in normal human serum and two corresponding antigenic types of myeloma 7S gamma globulins have been detected with rabbit anti-serums to proteins associated with pathological conditions, the differences being related to the H -chains of 7S gamma globulin. No relationship exists with type I and type II antigenic classification, determined by L-chains. Human serums with various hereditary gamma globulin (Gm) specificities contain both types of 7S gamma globulin.