An extremely effective DNA photocleavage utilizing functionalized liposomes with a fullerene-enriched lipid bilayer

An extremely effective DNA photocleavage utilizing functionalized liposomes with a fullerene-enriched lipid bilayer
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DOI:
10.1021/ja070243s
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发表时间:
2007-04-11
影响因子:
15
通讯作者:
Konishi, Toshifumi
Konishi, Toshifumi
中科院分区:
化学1区
文献类型:
--
作者:
Ikeda, Atsushi;Doi, Yuki;Konishi, Toshifumi

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以不稳定的富勒烯复合物C-70·γ-CDx为原料,通过交换反应合成了具有高C-70浓度的表面功能化脂质体(LMIC 70)。LMIC 70的DNA光切割能力远高于LMIC 60或C-60。
A surface-functionalized liposome with a high C-70 concentration (LMIC70) was synthesized by exchange reaction from an unstable fullerene complex, C-70.gamma-CDx. The DNA photocleavage ability of LMIC70 is extremely higher than that of LMIC60 or C-60.gamma-CDx.