Division of labor in the growth cone by DSCR1.
Division of labor in the growth cone by DSCR1.
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DOI：
10.1083/jcb.201605012
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发表时间：
2016-05-23
期刊：
影响因子：
--
通讯作者：
Gomez TM
中科院分区：
文献类型：
--
作者：
Catlett TS;Gomez TM
局部蛋白质合成指导新生轴突的生长锥转向，但在紧凑的、很大程度上自主的微环境中控制这一过程的机制仍然知之甚少。在本期中，Wang et al.（2016）。[j]细胞生物学。http://dx.doi.org/10.1083/jcb.201510107)表明钙调磷酸酶调节唐氏综合征关键区1蛋白调节基底神经突的生长和生长锥的转动。
Local protein synthesis directs growth cone turning of nascent axons, but mechanisms governing this process within compact, largely autonomous microenvironments remain poorly understood. In this issue, Wang et al. (2016. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201510107) demonstrate that the calcineurin regulator Down syndrome critical region 1 protein modulates both basal neurite outgrowth and growth cone turning.