EEG oscillatory states as neuro-phenomenology of consciousness as revealed from patients in vegetative and minimally conscious states
EEG oscillatory states as neuro-phenomenology of consciousness as revealed from patients in vegetative and minimally conscious states
复制标题
从植物人和微弱意识状态患者身上揭示作为意识神经现象学的脑电图振荡状态
DOI：
10.1016/j.concog.2011.10.004
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发表时间：
2012-03-01
影响因子：
2.4
通讯作者：
Galardi, Giuseppe
中科院分区：
文献类型：
--
作者：
Fingelkurts, Alexander A.;Fingelkurts, Andrew A.;Galardi, Giuseppe
本文探讨了静息脑电图（EEG）在揭示意识神经成分（NCC）中的价值。我们量化的动态剧目，持续时间和振荡类型的EEG微状态在闭眼休息的临床自我意识的表达程度。对于NCC，提出了一种模型，将正常、严重干扰的意识状态和无意识状态进行对比。使用意识障碍患者。结果表明，在静息状态下的脑电微状态的剧目，持续时间和振荡类型定量相关的意识表达的水平在脑损伤患者和健康意识的主题。具体而言，结果表明：（a）EEG微状态类型数量的减少与意识状态的改变相关，（B）无意识与EEG α节律微状态缺乏多样性相关，（c）δ、θ和慢α节律微状态的发生概率和持续时间与无意识相关，而快速α节律微状态的发生概率和持续时间与意识有关。结论：静息脑电图对NCC的诊断具有潜在价值。这项工作可能对意识障碍患者的临床护理和医疗法律决策产生影响。(C)2011 Elsevier Inc. All rights reserved.
The value of resting electroencephalogram (EEG) in revealing neural constitutes of consciousness (NCC) was examined. We quantified the dynamic repertoire, duration and oscillatory type of EEG microstates in eyes-closed rest in relation to the degree of expression of clinical self-consciousness. For NCC a model was suggested that contrasted normal, severely disturbed state of consciousness and state without consciousness. Patients with disorders of consciousness were used. Results suggested that the repertoire, duration and oscillatory type of EEG microstates in resting condition quantitatively related to the level of consciousness expression in brain-damaged patients and healthy-conscious subjects. Specifically, results demonstrated that (a) decreased number of EEG microstate types was associated with altered states of consciousness, (b) unawareness was associated with the lack of diversity in EEG alpha-rhythmic microstates, and (c) the probability for the occurrence and duration of delta-, theta- and slow-alpha-rhythmic microstates were associated with unawareness, whereas the probability for the occurrence and duration of fast-alpha-rhythmic microstates were associated with consciousness. In conclusion, resting EEG has a potential value in revealing NCC. This work may have implications for clinical care and medical-legal decisions in patients with disorders of consciousness. (C) 2011 Elsevier Inc. All rights reserved.