The structure of fine splenic arterial vessels in relation to hemoconcentration and red cell destruction.
The structure of fine splenic arterial vessels in relation to hemoconcentration and red cell destruction.
复制标题
脾细动脉结构与血液浓缩和红细胞破坏的关系。
DOI：
10.1002/aja.1001110203
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发表时间：
1962
期刊：
影响因子：
--
通讯作者：
L. Weiss
中科院分区：
文献类型：
--
作者：
L. Weiss
材料与方法：动物。取14只体重约2 ~ 3kg、8月龄的正常新西兰白化兔和4只体重约10 ~ 12kg的正常杂种狗的脾脏。另外，研究了2只相似的狗和4只相似的兔子在给予Thorotrast后。麻醉。将家兔置于2 - 3ml的手术麻醉下。Nembutal （Veterinary Nembutal 60mg /ml, Abbott Co., Chicago）以0.5 - 1.0 ml的剂量腹腔注射，持续两小时。麻醉犬先腹腔注射6 ~ 8ml奈布妥，然后静脉注射4 ~ 7ml。这种二氧化钍制剂在手术麻醉下静脉注射给药。两只狗在给予7ml胸腔造影45分钟后取出脾脏；在两只狗身上，在7毫升胸腔造影剂后5分钟。2只兔给予5 ml胸腔造影剂，45分钟后切除脾脏。在另一对给予5毫升胸腔造影剂，5分钟后进行脾切除术。Thorotrast是从纽约海登化学公司获得的
MATERIALS AND METHODSAnimals. Spleens were obtained from 14 normal New Zealand albino rabbits, each about 2 to 3 kg in weight and about eight months of age, and from four normal mongrel dogs about 10 to 12 kg in weight. Additionally, two similar dogs and four similar rabbits were studied after the administration of Thorotrast. Anesthesia. Rabbits were placed under surgical anesthesia by means of 2 to 3 ml. Nembutal (Veterinary Nembutal 60 mgm/ml Abbott Co., Chicago) administered intraperitoneally in 0.5 to 1.0 ml doses over a period of two hours. Dogs were anesthetized with 6 to 8 ml. Nembutal intraperitoneally, and then 4 to 7 ml intravenously.Thorotrast. This preparation of thorium dioxide was administered intravenously in animals under surgical anesthesia. In two dogs the spleen was taken out 45 minutes after the administration of 7 ml of Thorotrast; in two dogs, five minutes after 7 ml Thorotrast. Two rabbits were given 5 ml Thorotrast and the spleen removed after 45 minutes. In an-other pair given 5 ml Thorotrast, five minutes elapsed before splenectomy. The Thorotrast was obtained from Heyden Chemical Corp., NY