Helmet mold-based surface brachytherapy for homogeneous scalp treatment: A case report
Helmet mold-based surface brachytherapy for homogeneous scalp treatment: A case report
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DOI：
10.1007/s00066-007-1648-7
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发表时间：
2007-04-01
影响因子：
3.1
通讯作者：
Hildebrandt, Guido
中科院分区：
文献类型：
--
作者：
Liebmann, Andre;Pohlmann, Stefan;Hildebrandt, Guido
背景/病例报告：复杂形状区域的外射束放射治疗有时很难实现。在患有慢性淋巴性白血病（CLL）浸润整个头皮皮肤的患者中，使用电子或光子的常规外射束放射治疗无法充分治疗目标。因此，作者开发了一种近距离放射治疗印模技术，使用定制头盔（聚乙烯）和柔性填隙塑料施源器，并使用Microselectron Ir-192 HDR（高剂量率）源非常均匀地照射目标（2.0戈伊每日分次; 36.0戈伊总剂量与3 mm焦点深度的参考点相关）。技术上的困难，CT支持的三维适形治疗计划，和验证与CT探头测量。治疗耐受性良好，并导致完全局部缓解的CLL infiltration在后续的30 months.Conclusion：提出的治疗淋巴瘤infiltration在头皮HDR印模技术是特殊的，但安全和可行的，以实现局部肿瘤控制。
Background/Case Report: External-beam radiotherapy of complex-shaped areas is sometimes difficult to realize. In a patient with chronic lymphatic leukemia (CLL) infiltrates of the skin of the whole scalp, conventional external-beam radiotherapy with electrons or photons was not able to treat the target sufficiently. Thus, the authors developed a brachytherapy moulage technique using a customized helmet (polyethylene) with flexible interstitial plastic applicators and irradiated the target very homogeneously with a microselectron Ir-192 HDR (high-dose-rate) source (2.0 Gy daily fractionated; 36.0 Gy total dose related to the reference points in 3 mm focus depth). Technical difficulties, CT-supported three-dimensional conformal treatment planning, and verification with TLD probe measurements are described. The treatment was well tolerated and resulted in complete local remission of the CLL infiltrates within a follow-up of 30 months.Conclusion: The presented treatment of lymphoma infiltrates at the scalp by HDR moulage techniques is exceptional but safe and practicable to achieve local tumor control.