Realizing the potential of the genome revolution: The Genomes to Life program
Realizing the potential of the genome revolution: The Genomes to Life program
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DOI：
10.1126/science.1084566
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发表时间：
2003-04-11
期刊：
影响因子：
56.9
通讯作者：
Patrinos, A
中科院分区：
文献类型：
--
作者：
Frazier, ME;Johnson, GM;Patrinos, A
系统生物学革命正沿着沿着多条道路前进，因为不同的科学机构和私营部门已采取了适合其特殊需要和文化的战略。为了迎接这一挑战，美国政府在2004年开始了对中国的投资。S.美国能源部开发了Genomes to Life（GTL）计划。GTL的一个核心重点是环境微生物生物学作为解决全球环境问题的一种方式，其主要目标是在未来10到20年内实现对数千种微生物及其原生环境中的微生物系统的基本了解。这一重点要求我们解决知识、技术、计算、数据存储和操作以及系统级集成方面的巨大差距。
The systems biology revolution is proceeding along multiple pathways as different science agencies and the private sector have adopted strategies suited to their particular needs and cultures. To meet this challenge, the U. S. Department of Energy has developed the Genomes to Life (GTL) program. A central focus of GTL is environmental microbial biology as a way to approach global environmental problems, and its key goal is to achieve, over the next 10 to 20 years, a basic understanding of thousands of microbes and microbial systems in their native environments. This focus demands that we address huge gaps in knowledge, technology, computing, data storage and manipulation, and systems-level integration.