The impact of Michigan's Dr Ron Davis smoke-free air law on levels of cotinine, tobacco-specific lung carcinogen and severity of self-reported respiratory symptoms among non-smoking bar employees.
The impact of Michigan's Dr Ron Davis smoke-free air law on levels of cotinine, tobacco-specific lung carcinogen and severity of self-reported respiratory symptoms among non-smoking bar employees.
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密歇根州罗恩·戴维斯博士无烟空气法对非吸烟酒吧员工中可替宁、烟草特有的肺癌致癌物水平以及自我报告的呼吸道症状严重程度的影响。
DOI：
10.1136/tobaccocontrol-2011-050328
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发表时间：
2012
期刊：
影响因子：
5.2
通讯作者：
Kiley,Janet
中科院分区：
文献类型：
--
作者：
Wilson,Teri;Shamo,Farid;Boynton,Katherine;Kiley,Janet
目的了解2010年5月1日生效的密歇根州罗恩·戴维斯博士无烟空气法实施前后对酒吧从业人员健康和二手烟暴露(SHS)的影响。故事背景是密歇根州12个县的酒吧。研究对象是酒吧员工，通过传单和与当地卫生部门工作人员的个别讨论招募他们。参与者完成了一份筛选问卷，以确定资格。共有40名符合条件的员工完成了人口学调查，提供了尿样用于可替宁和4-(甲基亚硝基)-1-(3-吡啶)-1-丁醇的分析，并在法律生效前6 周和法律生效后6-10 周完成了呼吸和一般健康状况的问卷调查。主要观察指标为尿样中的总可替宁和总NNAL，以及在法律实施前和法律实施后的研究期间收集的自制呼吸系统和一般健康状况问卷的数据。结果法律实施2个月后，可替宁平均水平从35.9pmoL/ml降至不可量化的值(p<；0.001)，平均NNAL水平从0.086 pmol/ml降至0.034 pmol/ml(p<；0.001) 。所有6种自我报告的呼吸道症状(P<；0.001)和一般健康状况(P<；0.001)也都有显著改善。结论SHS生物标志物可替宁和NNAL的减少以及报告的呼吸健康改善表明，密歇根州无烟工作场所法律正在保护酒吧员工的健康。
ObjectiveTo determine the impact on bar employee's health and exposure to secondhand smoke (SHS) before and after the implementation of Michigan's Dr Ron Davis smoke-free air law that went into effect on 1 May 2010, prohibiting smoking in places of work, including bars.MethodsThis study used a pre/postintervention experimental design. The setting was bars in 12 Michigan counties. Subjects were bar employees, recruited through flyers and individual discussions with local health department staff. Participants completed a screening questionnaire to determine eligibility. A total of 40 eligible employees completed a demographic survey, provided urine samples for analysis of cotinine and 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) and completed questionnaires on respiratory and general health status 6 weeks before and 6–10 weeks after the law went into effect. The main outcome measures were urine samples for total cotinine and total NNAL and data from a self-administered respiratory and general health status questionnaire collected during the pre-law and post-law study periods.ResultsThere was a significant decrease in the mean cotinine levels from 35.9 ng/ml to a non-quantifiable value (p<0.001), and there was a significant reduction in the mean NNAL level from 0.086 pmol/ml to 0.034 pmol/ml (p<0.001) 2 months after implementation of the law. There was also a significant improvement in all six self-reported respiratory symptoms (p<0.001) and general health status (p<0.001).ConclusionsThe reduction in the SHS biomarkers cotinine and NNAL and reported improvement in respiratory health demonstrates that the Michigan smoke-free workplace law is protecting bar employee health.