Myocardial ischemia in acute coronary syndrome: assessment using 64-MDCT.
Myocardial ischemia in acute coronary syndrome: assessment using 64-MDCT.
复制标题
急性冠状动脉综合征中的心肌缺血：使用 64-MDCT 进行评估。
DOI：
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发表时间：
2009
期刊：
影响因子：
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通讯作者：
Susumu Shigemi
中科院分区：
文献类型：
--
作者：
M. Nagao;H. Matsuoka;H. Kawakami;H. Higashino;T. Mochizuki;Masahiko Uemura;Susumu Shigemi
目的
我们研究了64层螺旋CT心肌成像在急性冠状动脉综合征（ACS）心肌缺血评估中的性能。
材料和方法
对35例ACS患者进行了心脏CT检查，其中急性心肌梗死（AMI）24例，不稳定型心绞痛（UAP）11例。我们使用与冠状动脉CT血管造影相同的原始数据重建舒张期和收缩期的2D心肌图像。心肌中的CT数被用作缺血的估计。心肌用彩色标度显示，比灰度更清楚地描绘微弱的低密度区域。我们评估了罪犯病变范围内心动周期内心肌增强的变化。此外，我们根据心肌增强的透壁性对患者进行分类，并检查此特征是否与心肌损伤相关。
结果
91%的ACS患者、96%的AMI患者和75%的UAP患者的心脏收缩期心肌显像显示罪犯病变区域的心肌低增强。收缩期低增强区较舒张期广泛。心肌生物标志物显示，收缩期低增强的透壁程度与心肌损伤相关。
结论
CT心肌显像对ACS相关部位心肌缺血的评价具有较高的敏感性。
OBJECTIVE
We investigated the performance of 64-MDCT myocardial imaging in assessing myocardial ischemia in acute coronary syndrome (ACS).
MATERIALS AND METHODS
Cardiac CT was performed in 35 patients with ACS: 24 patients with acute myocardial infarction (AMI) and 11 patients with unstable angina pectoris (UAP). We reconstructed 2D myocardial images at diastolic and systolic phases using the same raw data as those used for coronary CT angiography. The CT number in the myocardium was used as an estimate of ischemia. The myocardium was shown using a color scale that depicts faint low-density areas more clearly than gray scale. We evaluated the variations in myocardial enhancement during the cardiac cycle in the territory of the culprit lesion. In addition, we classified patients on the basis of the transmurality of myocardial enhancement and examined whether this feature correlates with myocardial damage.
RESULTS
Myocardial imaging at systole showed myocardial hypoenhancement in territories of the culprit lesion in 91% of patients with ACS, 96% of patients with AMI, and 75% of patients with UAP. The hypoenhancement areas at systole tended to be more extensive than those at diastole. The transmural extent of hypoenhancement at systole correlated with myocardial damage, which was shown by myocardial biomarkers.
CONCLUSION
CT myocardial imaging can be used to assess myocardial ischemia in the appropriate region of ACS with high sensitivity.
影响因子：
20.1
作者：
CHILIAN, WM
通讯作者：
CHILIAN, WM
影响因子：
3.3
作者：
Ferencik, M;Nomura, CH;Brady, TJ
通讯作者：
Brady, TJ
影响因子：
24
作者：
Hoffmann, U;Moselewski, F;Brady, TJ
通讯作者：
Brady, TJ