特集 脳神経外科医が知っておきたい-てんかんのすべて Ⅳ 脳神経外科医が知っておきたいてんかん治療 植え込み型電気刺激療法
特集 脳神経外科医が知っておきたい-てんかんのすべて Ⅳ 脳神経外科医が知っておきたいてんかん治療 植え込み型電気刺激療法
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专题:神经外科医生需要了解的关于癫痫的一切 Ⅳ 神经外科医生需要了解的癫痫治疗:植入式电刺激疗法
DOI:
10.11477/mf.1436204725
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发表时间:
2023
期刊:
影响因子:
--
通讯作者:
菅野 秀宣
中科院分区:
文献类型:
--
作者:
松田勇輝;平松匡文;杉生憲志;木村 颯;山岡陽子;胡谷侑貴;佐藤 悠;西 和彦;村井 智;春間 純;菱川朋人;伊達 勲;菅野 秀宣
Neuromodulation therapy for epilepsy is the third treatment option after medical treatment with antiepileptic drugs and surgical treatment, such as epileptic focal resection. In addition to vagus nerve stimulation(VNS), deep brain stimulation(DBS)and responsive neurostimulation(RNS)have been approved in several countries. These therapies consist of an implantable device and stimulating electrodes. These therapies have great potential to reduce seizure frequency and severity, improve patients' quality of life, and maintain therapeutic efficacy. When VNS was first introduced, electrical stimulation was set at regular intervals. However, current devices have introduced closed-loop therapy, in which stimulation is performed by detecting seizures. Multi-mode stimulation settings have also been introduced in VNS to adjust patient's seizure characteristics based on the time of the day when seizures are most likely to occur. This review describes the third therapeutic approach for the treatment of epilepsy based on recent research reports.