SnapShot: CRISPR-RNA-guided adaptive immune systems.
SnapShot: CRISPR-RNA-guided adaptive immune systems.
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DOI：
10.1016/j.cell.2015.09.011
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发表时间：
2015-09-24
期刊：
影响因子：
64.5
通讯作者：
Wiedenheft B
中科院分区：
文献类型：
--
作者：
Carter J;Wiedenheft B
细菌和古菌已经进化出复杂的适应性免疫系统，这些免疫系统依赖于CRISPR基因座和不同的Cas基因盒，这些基因被分为三个主要类型和至少11个亚型。所有CRISPR-CAS免疫系统都经历了三个主要阶段：获得、生物发生和干扰。这张快照总结了我们目前对这些令人着迷的免疫系统的了解。要查看此快照，请打开或下载PDF。
Bacteria and archaea have evolved sophisticated adaptive immune systems that reply on CRISPR loci and a diverse cassette of Cas genes that are classified into three main types and at least eleven subtypes. All CRISPR-Cas immune systems operate through three main stages: acquisition, biogenesis, and interference. This SnapShot summarizes our current knowledge of these fascinating immune systems. To view this SnapShot, open or download the PDF.