Higher Viral Load of Emerging Norovirus GII.P16-GII.2 than Pandemic GII.4 and Epidemic GII.17, Hong Kong, China
Higher Viral Load of Emerging Norovirus GII.P16-GII.2 than Pandemic GII.4 and Epidemic GII.17, Hong Kong, China
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DOI：
10.3201/eid2501.180395
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发表时间：
2019-01-01
影响因子：
11.8
通讯作者：
Chan, Martin Chi-Wai
中科院分区：
文献类型：
--
作者：
Cheung, Sarah K. C.;Kwok, Kirsty;Chan, Martin Chi-Wai
我们比较了香港住院患者中新出现的重组诺如病毒GII P16-GII.2与大流行GII Pe-GII 4和大流行GII P17-GII 17的病毒载量。在不同年龄组中，GII、P16-GII.2的病毒载量均高于其他基因。GII.P16-GII.2与大流行基因一样具有复制能力，这解释了其高传播性和广泛传播。
We compared viral load of emerging recombinant norovirus GII.P16-GII.2 with those for pandemic GII.Pe-GII.4 and epidemic GII.P17-GII.17 genotypes among inpatients in Hong Kong. Viral load of GII.P16-GII.2 was higher than those for other genotypes in different age groups. GII.P16-GII.2 is as replication competent as the pandemic genotype, explaining its high transmissibility and widespread circulation.