EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis
EIN2, a bifunctional transducer of ethylene and stress responses in Arabidopsis
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DOI：
10.1126/science.284.5423.2148
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发表时间：
1999-06-25
期刊：
影响因子：
56.9
通讯作者：
Ecker, JR
中科院分区：
文献类型：
--
作者：
Alonso, JM;Hirayama, T;Ecker, JR
乙烯调节植物生长、发育和对各种胁迫的反应。拟南芥 EIN2 基因的克隆鉴定了乙烯信号通路的一个核心组成部分。 EIN2 的氨基末端整合膜结构域与疾病相关的金属离子转运蛋白 Nramp 家族相似。 EIN2 CEND 的表达足以组成型激活乙烯反应并恢复突变植物对茉莉酸和百草枯诱导的氧自由基的反应性。因此，EIN2 被认为是先前不同的激素反应途径之间的分子联系。植物可以通过使用一组共同的信号分子来使用组合机制来评估各种胁迫。
Ethylene regulates plant growth, development, and responsiveness to a variety of stresses. Cloning of the Arabidopsis EIN2 gene identifies a central component: of the ethylene signaling pathway. The amino-terminal integral membrane domain of EIN2 shows similarity to the disease-related Nramp family of metal-ion transporters. Expression of the EIN2 CEND is sufficient to constitutively activate ethylene responses and restores responsiveness to jasmonic acid and paraquat-induced oxygen radicals to mutant plants. EIN2 is thus recognized as a molecular link between previously distinct hormone response pathways. plants may use a combinatorial mechanism for assessing various stresses by enlisting a common set of signaling molecules.