Understanding patient and physician perceptions of benign prostatic hyperplasia in Europe: The Prostate Research on Behaviour and Education (PROBE) Survey
Understanding patient and physician perceptions of benign prostatic hyperplasia in Europe: The Prostate Research on Behaviour and Education (PROBE) Survey
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DOI：
10.1111/j.1742-1241.2007.01635.x
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发表时间：
2008-01-01
影响因子：
2.6
通讯作者：
de la Rosette, J.
中科院分区：
文献类型：
--
作者：
Emberton, M.;Marberger, M.;de la Rosette, J.
目的：良性前列腺增生（BPH）是一种令人烦恼的疾病，如果不及时治疗，可能会进展。然而，患者和泌尿科医生对BPH管理的观点尚未完全理解。前列腺行为和教育研究（PROBE）调查的目的是评估502例BPH患者的求医行为和对BPH治疗的态度，以及来自法国、德国、意大利、西班牙和英国的100名泌尿科医生的信念和管理实践。结果：患者就医的主要顾虑是癌症恐惧、睡眠障碍、不适或尴尬。大多数BPH患者回忆接受直肠指检（61%），常规前列腺特异性抗原（PSA）检测（67%）和处方药（72%）。80%的5 α-还原酶抑制剂（5ARI）使用者对他们的治疗感到满意，而α-受体阻滞剂使用者为68%。超过一半的患者担心需要手术或发生急性尿潴留，超过75%的患者更喜欢降低手术风险的药物，而不是快速缓解症状的药物。大多数泌尿科医生对> 90%的BPH症状患者进行直肠指检（96%）和PSA检测（71%）。87%的泌尿科医生认为BPH进展，78%的人认为5ARI可以预防BPH进展。然而，大多数泌尿科医生处方α-受体阻滞剂，而很少有人处方5ARI。结论：这项研究强调了欧洲前列腺增生患者和医生的观点和信念与当前实践之间的差异。
Aims: Benign prostatic hyperplasia (BPH) is a bothersome disease that can progress if left untreated. However, patient and urologist perspectives on BPH management are not fully understood. The aim of the Prostate Research on Behaviour and Education (PROBE) Survey was to assess healthcare-seeking behaviour and attitudes to BPH treatment in 502 BPH patients, and the beliefs and management practices of 100 urologists, from France, Germany, Italy, Spain and the UK. Results: The principal concerns of patients seeking medical advice were fear of cancer, sleep disruption, discomfort or embarrassment. The majority of BPH patients recalled receiving a digital rectal examination (61%), routine prostate-specific antigen (PSA) tests (67%) and prescription medication (72%). Eighty per cent of 5 alpha-reductase inhibitor (5ARI) users vs. 68% of alpha-blocker users were satisfied with their treatment. More than half of the patients were concerned about requiring surgery or developing acute urinary retention, and > 75% would prefer a drug that provides reduction in the risk of surgery than one that provides rapid symptom relief. Most urologists performed digital rectal examinations (96%) and PSA tests (71%) on > 90% of patients presenting with BPH symptoms. Eighty-seven per cent of urologists believe that BPH progresses, and 78% believe that 5ARIs prevent BPH progression. However, most urologists prescribe alpha-blockers while few prescribe 5ARIs. Conclusions: This study highlights discrepancies between views and beliefs of patients and physicians regarding BPH and current practice in Europe.