pH-Responsive Nanogated Ensemble Based on Gold-Capped Mesoporous Silica through an Acid-Labile Acetal Linker

pH-Responsive Nanogated Ensemble Based on Gold-Capped Mesoporous Silica through an Acid-Labile Acetal Linker
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DOI:
10.1021/ja907838s
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发表时间:
2010-02-10
影响因子:
15
通讯作者:
Feng, Pingyun
Feng, Pingyun
中科院分区:
化学1区
文献类型:
--
作者:
Liu, Rui;Zhang, Ying;Feng, Pingyun

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利用缩醛基团连接的金纳米粒子修饰介孔二氧化硅,开发了一种新的pH响应性杂化纳米门系综。在酸性环境中缩醛连接基的水解使得金纳米颗粒作为看门人来控制客体分子在不同pH下从介孔二氧化硅中的释放。
A new pH-responsive hybrid nanogated ensemble has been developed by using acetal group linked gold nanoparticle capped mesoporous silica. The hydrolysis of acetal linker at acidic environment makes the gold nanoparticles work as a gatekeeper to control the release Of guest molecules from mesoporous silica under different pH's.