Characteristics and Prognostic Factors of Venous Thromboembolism in Cancer Patients.
Characteristics and Prognostic Factors of Venous Thromboembolism in Cancer Patients.
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癌症患者静脉血栓栓塞的特征和预后因素。
DOI：
10.3400/avd.oa.22-00036
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发表时间：
2022-06-25
影响因子：
0.8
通讯作者：
中科院分区：
文献类型：
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作者：
背景：改善恶性肿瘤患者的预后增加了发生静脉血栓栓塞的患者数量。我们研究了癌症VTE患者的特征和预后因素。方法：我们从2005年4月至2018年3月诊断了725例VTE患者。有322例癌症相关患者（CAT）和403例非癌症相关患者（nonCAT）。我们研究了CAT患者VTE的特征和预后因素。结果：有156名妇女和166名男子在CAT，132名妇女和271名男子在非CAT。血栓近端部位无明显差异。当将部位分为左腿、右腿和双侧时，CAT组中双侧病例更常见。比较CAT组VTE诊断后的总生存率，沿着癌症转移和复发的高D-二聚体水平（> 6 µg/mL）患者的预后较差。结论：多种VTE因素可预测CAT患者的预后，CAT在癌症患者的治疗中具有重要意义。(This是来自Jpn J Phlebol 2020; 31（3）：153-159的第二出版物。
Background: Improving the prognosis of patients with malignant tumors is increasing the number of patients who develop venous thromboembolism. We examined the characteristics and prognostic factors of VTE patients with cancer. Methods: We diagnosed 725 VTE patients from April 2005 to March 2018. There were 322 cancer associated patients (CAT) and 403 non-cancer associated patients (nonCAT). We examined characteristics and prognostic factors of VTE in CAT patients. Results: There were 156 women and 166 men in CAT, and 132 women and 271 men in nonCAT. There was no significant difference in the location of proximal portion of thrombus. When locations were divided into left leg, right leg, and bilateral legs, bilateral cases were more common in CAT group. Comparing the overall survival after VTE diagnosis in the CAT group, the prognosis was poor in patients with high D-dimer level (≧6 µg/mL) along with cancer metastasis and recurrence. Conclusions: Various VTE factors predict prognosis in CAT patients, and CAT is important in the treatment of cancer patients. (This is secondary publication from Jpn J Phlebol 2020; 31(3): 153–159.)