ORegAnno 3.0: a community-driven resource for curated regulatory annotation.
ORegAnno 3.0: a community-driven resource for curated regulatory annotation.
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Oreganno 3.0：一种社区驱动的用于策划监管注释的资源。
DOI：
10.1093/nar/gkv1203
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发表时间：
2016-01-04
影响因子：
14.9
通讯作者：
Open Regulatory Annotation Consortium
中科院分区：
文献类型：
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作者：
Lesurf R;Cotto KC;Wang G;Griffith M;Kasaian K;Jones SJ;Montgomery SB;Griffith OL;Open Regulatory Annotation Consortium
Open Regulatory Annotation数据库（ORegAnno）是一个管理监管注释的资源。它包含有关调控区、转录因子结合位点、RNA结合位点、调控变体、单倍型和其他调控元件的信息。ORegAnno通过促进来自文献和高度策划的资源的监管观察的众包解释和注释，将自己与其他监管资源区分开来。它包含一个全面的注释方案，旨在描述监管事件的要素和结果。此外，ORegAnno将这些不同的数据源和注释汇集到一个单一的高质量监管信息目录中。目前的版本是NAR数据库问题中以前的数据库的更新，现在包含18个物种的1948307条记录，总覆盖范围为334215080 bp。完整的记录、注释和其他相关数据可在www.example.com上浏览和下载。
The Open Regulatory Annotation database (ORegAnno) is a resource for curated regulatory annotation. It contains information about regulatory regions, transcription factor binding sites, RNA binding sites, regulatory variants, haplotypes, and other regulatory elements. ORegAnno differentiates itself from other regulatory resources by facilitating crowd-sourced interpretation and annotation of regulatory observations from the literature and highly curated resources. It contains a comprehensive annotation scheme that aims to describe both the elements and outcomes of regulatory events. Moreover, ORegAnno assembles these disparate data sources and annotations into a single, high quality catalogue of curated regulatory information. The current release is an update of the database previously featured in the NAR Database Issue, and now contains 1 948 307 records, across 18 species, with a combined coverage of 334 215 080 bp. Complete records, annotation, and other associated data are available for browsing and download at http://www.oreganno.org/.