Terpenes from Forests and Human Health.
Terpenes from Forests and Human Health.
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DOI：
10.5487/tr.2017.33.2.097
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发表时间：
2017-04
影响因子：
2.3
通讯作者：
Lee IS
中科院分区：
文献类型：
--
作者：
Cho KS;Lim YR;Lee K;Lee J;Lee JH;Lee IS
森林浴通过森林气溶胶的沐浴和身体放松对人类健康有有益的影响。由多个异戊二烯单元组成的萜烯是各种植物产生的最大一类有机化合物，也是森林气溶胶的主要成分之一。传统上，含萜烯的植物油被用于治疗各种疾病，而不知道具体的生物活性化合物的确切功能或作用机制。本文从抗炎、抗肿瘤、神经保护等方面对从森林中提取的萜类化合物进行了分类。此外，还讨论了在各种体内和体外系统中描述的单个萜烯的潜在作用机制及其对这些过程的影响。总之，显示萜烯生物学效力的研究支持了森林浴的益处，并提出了将萜烯用作治疗各种人类疾病的化学治疗剂的潜在用途。
Forest bathing has beneficial effects on human health via showering of forest aerosols as well as physical relaxation. Terpenes that consist of multiple isoprene units are the largest class of organic compounds produced by various plants, and one of the major components of forest aerosols. Traditionally, terpene-containing plant oil has been used to treat various diseases without knowing the exact functions or the mechanisms of action of the individual bioactive compounds. This review categorizes various terpenes easily obtained from forests according to their anti-inflammatory, anti-tumorigenic, or neuroprotective activities. Moreover, potential action mechanisms of the individual terpenes and their effects on such processes, which are described in various in vivo and in vitro systems, are discussed. In conclusion, the studies that show the biological effectiveness of terpenes support the benefits of forest bathing and propose a potential use of terpenes as chemotherapeutic agents for treating various human diseases.