Bacteruria with group-B streptococcus: is it a risk factor for adverse pregnancy outcomes?
Bacteruria with group-B streptococcus: is it a risk factor for adverse pregnancy outcomes?
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DOI：
10.3109/14767058.2012.671872
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发表时间：
2012-10-01
影响因子：
1.8
通讯作者：
Sheiner, Eyal
中科院分区：
文献类型：
--
作者：
Kessous, Roy;Weintraub, Adi Y.;Sheiner, Eyal
目的：调查患有和不患有 B 族链球菌 (GBS) 菌尿的患者的妊娠结局。方法：进行一项回顾性研究，比较妊娠期 GBS 菌尿、GBS 阴道培养阳性和妊娠期无 GBS 定植的女性的妊娠结局。结果：发现产时发热（U-GBS 0.5%，V-GBS 0.3%，无 GBS 0.1%，p = 0.001）和绒毛膜羊膜炎（U-GBS 3.3%，V-GBS 1%，无 GBS 0.7%，p = 0.001）之间存在显着的线性相关性。此外，与无 GBS 组相比，U-GBS 组的早产率（15.3% vs. 7.9%，p = 0.001）和胎膜早破（10.7% vs. 7.9，p = 0.001）显着较高。患有 U-GBS 的女性患糖尿病、高血压和习惯性流产的几率较高，而且宫内生长受限 (IUGR) 的风险也较高。此外，U-GBS 患者更频繁地接受引产和剖宫产。结论：我们的研究表明 U-GBS 与不良产科结局之间存在显着关联。此外，GBS 培养位置与产科并发症之间存在线性关联。然而，GBS 与我们人群的不良围产期结局无关。
Objective: To investigate pregnancy outcomes of patients with and without group-B streptococcus (GBS) bacteriuria. Methods: A retrospective study comparing pregnancy outcomes of women with GBS bacteriuria during pregnancy, those with positive GBS vaginal cultures and those without GBS colonization during pregnancy was conducted. Results: A significant linear association was found with regard to intrapartum fever (U-GBS 0.5%, V-GBS 0.3%, no GBS 0.1%, p = 0.001) and chorioamnionitis (U-GBS 3.3%, V-GBS 1%, no GBS 0.7%, p = 0.001). In addition preterm delivery (15.3% vs. 7.9%, p = 0.001) and premature rupture of membranes (10.7% vs. 7.9, p = 0.001) were significantly higher in the U-GBS group compared to no GBS. Woman with U-GBS had higher rates of diabetes mellitus, hypertensive disorders, and habitual abortions as well as a higher risk for intrauterine growth restriction (IUGR). In addition patients with U-GBS underwent induction of labor and cesarean delivery more frequently. Conclusions: Our study showed a significant association between U-GBS and adverse obstetrical outcomes. In addition a linear association was found between GBS culture location and obstetric complications. However, GBS was not associated with adverse perinatal outcome in our population.