Effects of exposure of animals to ultra-wideband pulses

Effects of exposure of animals to ultra-wideband pulses
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DOI:
10.1097/01.hp.0000256780.23536.15
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发表时间:
2007-06-01
期刊:
影响因子:
2.2
通讯作者:
Seaman, Ronald L.
Seaman, Ronald L.
中科院分区:
医学4区
文献类型:
--
作者:
Seaman, Ronald L.

文献摘要

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综述了超宽带(UWB)脉冲对整个动物的生物学效应。已发表研究的条件和结果按暴露类型分组:自由场、平行板传输线和千兆横向电磁室(GTEM)。这些研究调查了不同实验动物(主要是啮齿动物)的心血管系统、神经系统、畸形学、肿瘤产生和遗传毒性。根据研究,脉冲的峰值电场为10至250 kV m(-1),持续时间为0.8至8 ns,上升时间为140至340 ps。在大多数情况下,暴露和未暴露的动物之间只有很小的差异,有时是虚假的。在回顾的研究中,与一氧化氮合酶抑制剂的相互作用和对长期血压的影响具有统计学意义。
Publications reporting biological effects of wholeanimal exposures to ultra-wideband (UWB) pulses are reviewed. Conditions and results of the published studies are grouped by type of exposure: free-field, parallel-plate transmission line, and giga transverse electromagnetic cell (GTEM). The studies investigated the cardiovascular system, the nervous system, teratology, tumor production, and genotoxicity in different experimental animals, primarily rodents. Depending on the study, pulses had peak electric fields of 10 to 250 kV m(-1), durations of 0.8 to 8 ns, and rise times between 140 and 340 ps. In most cases only small, sometimes spurious, differences between exposed and nonexposed animals were seen. Effects on interaction with an inhibitor of nitric oxide synthase and on long-term blood pressure were statistically significant in the studies reviewed.