Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2)
Hopanoids are formed during transition from substrate to aerial hyphae in Streptomyces coelicolor A3(2)
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DOI：
10.1016/s0378-1097(00)00259-7
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发表时间：
2000-08-01
影响因子：
2.1
通讯作者：
Härtner, T
中科院分区：
文献类型：
--
作者：
Poralla, K;Muth, G;Härtner, T
天蓝色链霉菌A3（2）含有一组推定的类异戊二烯和类藿烷生物合成基因。该菌株在液体培养中不产生五环类霍帕烷，但在固体培养基上形成孢子时产生它们。在气生菌丝体和孢子的形成上有缺陷的突变体（bld），除了bldB之外，不合成hopanoids，而形成气生菌丝体但不合成孢子的突变体（whi）则合成hopanoids。膜浓缩类Hopanoids可能通过减少跨膜的水渗透性来减轻气生菌丝体中的胁迫。(C)2000年，欧洲微生物学会联合会。由Elsevier Science B.V.出版，版权所有。
Streptomyces coelicolor A3(2) contains a cluster of putative isoprenoid and hopanoid biosynthetic genes. The strain does not produce the pentacyclic hopanoids in liquid culture but produces them on solid medium when sporulating. Mutants defective in the formation of aerial mycelium and spores (bld), with the exception of bldB, do not synthesize hopanoids, whereas mutants, which form aerial mycelium but no spores (whi), do. The membrane condensing hopanoids possibly may alleviate stress in aerial mycelium by diminishing water permeability across the membrane. (C) 2000 Federation of European Microbiological Societies. Published by Elsevier Science B.V. All rights reserved.