Inhibiting BRD4 to generate BETter T cell memory.
Inhibiting BRD4 to generate BETter T cell memory.
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DOI:
10.1084/jem.20210877
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发表时间:
2021-08-02
期刊:
影响因子:
--
通讯作者:
Cui W
中科院分区:
文献类型:
--
作者:
Kasmani MY;Cui W
BRD4 is a bromodomain-containing protein that binds acetylated histones to regulate transcription. In this issue of JEM, Milner et al. show that BRD4 plays a critical role in the effector function of CD8 T cells responding to infection and cancer. BRD4 is a bromodomain-containing protein that binds acetylated histones to regulate transcription. In this issue of JEM, Milner et al. (2021. J. Exp. Med. https://doi.org/10.1084/jem.20202512) show that BRD4 plays a critical role in the effector function of CD8 T cells responding to infection and cancer.
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