Decoupled maternal and zygotic genetic effects shape the evolution of development
Decoupled maternal and zygotic genetic effects shape the evolution of development
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DOI：
10.7554/elife.37143
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发表时间：
2018-09-10
期刊：
影响因子：
7.7
通讯作者：
Rockman, Matthew V.
中科院分区：
文献类型：
--
作者：
Zakas, Christina;Deutscher, Jennifer M.;Rockman, Matthew V.
从间接发展到直接发展的进化转变涉及母体和合子遗传因素的变化，具有独特的群体遗传影响，但缺乏关于这种转变的遗传学的经验数据。多毛类Streblospio benedicti提供了一个机会，解剖一个重大的转变，在发展模式，使用正向遗传学。该物种的雌性产生发育成浮游幼虫的小卵或发育成底栖幼鱼的大卵。我们确定的大效应位点，母性影响幼虫的大小和独立的，不连锁的大效应位点，合子影响幼虫形态的离散方面。合子等位基因的可能适应性取决于它们的母体背景，产生正的频率依赖性，可能使当地种群同质化。发育遗传学和种群遗传学相互作用，塑造幼虫的进化。
Evolutionary transitions from indirect to direct development involve changes in both maternal and zygotic genetic factors, with distinctive population-genetic implications, but empirical data on the genetics of such transitions are lacking. The polychaete Streblospio benedicti provides an opportunity to dissect a major transition in developmental mode using forward genetics. Females in this species produce either small eggs that develop into planktonic larvae or large eggs that develop into benthic juveniles. We identify large-effect loci that act maternally to influence larval size and independent, unlinked large-effect loci that act zygotically to affect discrete aspects of larval morphology. The likely fitness of zygotic alleles depends on their maternal background, creating a positive frequency-dependence that may homogenize local populations. Developmental and population genetics interact to shape larval evolution.