Detection of Chlamydia trachomatis in tissue culture and cervical scrapings by in situ DNA hybridization.
Detection of Chlamydia trachomatis in tissue culture and cervical scrapings by in situ DNA hybridization.
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通过原位 DNA 杂交检测组织培养物和宫颈刮片中的沙眼衣原体。
DOI：
10.1093/infdis/153.6.1155
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发表时间：
1986
期刊：
影响因子：
--
通讯作者：
Quinn,TC
中科院分区：
文献类型：
--
作者：
Horn,JE;Hammer,ML;Falkow,S;Quinn,TC
沙眼衣原体是一种专性细胞内寄生虫，是最常见的性传播病原体之一[1]。由于高患病率和相关的后遗症，长期感染与C。沙眼，如不孕和宫外孕[2]，强烈建议对这种病原体进行常规筛查[3]。由于目前建议非怀孕妇女每年进行一次宫颈涂片进行细胞学筛查，而怀孕妇女在怀孕早期常规进行涂片[4]，因此在同一涂片上诊断衣原体的能力肯定是先进的。
Chlamydia trachomatis, an obligate intracellular parasite, is one of the most common sexually transmitted patho-gens [1]. Because of the high prevalence and associated sequelae of prolonged infection with C. trachomatis, such as infertility and ectopic pregnancy [2], routine screening for this pathogen has been strongly recommended [3]. Be-cause it is currently recommended that a nonpregnant woman have an annual cervical smear for cytological screening and that a pregnant woman have a smear taken routinely in early pregnancy [4], the ability to diagnose chlamydia on the same smear would certainly be advan-