School urinalysis screening in Korea: prevalence of chronic renal disease
School urinalysis screening in Korea: prevalence of chronic renal disease
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韩国学校尿液分析筛查：慢性肾病患病率
DOI：
10.1007/s004670100043
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发表时间：
2001
影响因子：
3
通讯作者：
H.
中科院分区：
文献类型：
--
作者：
B. Cho;S‐D. Kim;Y.M. Choi;H.
抽象的。自1998年以来，对韩国学童进行了大规模尿液筛查。我们分析了那些在学校筛查项目中显示异常尿液结果的患者。1998年1月至2000年1月期间，452名泌尿系统异常的儿童到庆熙大学医院儿科肾脏中心就诊。对患者的性别、年龄、24小时尿肌酐清除率、超声检查、多普勒扫描和肾活检进行回顾性分析。首次尿常规检查结果分为三组：单纯血尿组228例（50.4%），单纯蛋白尿组98例（21.7%），血尿和蛋白尿合并组79例（17.5%）。肾实质病变中伊加肾病占11.3%，系膜增生性肾炎占21.9%，其他占3.8%。在三组中，合并血尿和蛋白尿组的慢性肾脏疾病的发生率（57.7%）高于其他组。在所有访问受试者中，36.9%检测到慢性肾脏疾病。在学校筛查项目中，相当数量的患者表现出异常的尿液检查结果，这与慢性肾脏疾病相关，尤其是在合并血尿和蛋白尿组中。总之，大规模的尿液筛查试验应该是强制性的，以发现无症状的慢性肾脏疾病的学童。
Abstract. Since 1998, mass urine screening tests have been performed on Korean school children. We have analyzed those patients who showed abnormal urinary findings in the school screening program. Between January 1998 and January 2000, 452 children with abnormal urinary findings visited the Pediatric Kidney Center, Kyung-Hee University Hospital. Sex, age, 24-h urine creatinine clearance, ultrasonography, Doppler scans and renal biopsies were reviewed retrospectively. Results of initial urinalysis are divided into three groups: solely hematuria group (228 cases, 50.4%), solely proteinuria group (98 cases, 21.7%), and combined hematuria and proteinuria group (79 cases, 17.5%). Among the biopsied cases, the proportions representing renal parenchymal diseases were as follows: IgA nephropathy 11.3%, mesangial proliferative glomerulonephritis 21.9%, others 3.8%. Among the three groups, the combined hematuria and proteinuria group had more frequent chronic renal disease (57.7%) than the other groups. Chronic renal disease was detected in 36.9% of all visiting subjects. In the school screening program a significant number of patients showed abnormal urinary findings, which were associated with chronic renal diseases especially in the combined hematuria and proteinuria group. In conclusion, mass urine screening tests should be mandatory to detect asymptomatic chronic renal disease in school children.