Special delivery from mitochondria to peroxisomes.
Special delivery from mitochondria to peroxisomes.
复制标题
从线粒体到过氧化物酶体的特殊传递。
DOI：
10.1016/j.tcb.2008.04.002
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发表时间：
2008
影响因子：
19
通讯作者：
Subramani,Suresh
中科院分区：
文献类型：
--
作者：
Schumann,Uwe;Subramani,Suresh
细胞器间的通讯和相互作用是将生化功能分离到亚细胞器中的必要和公认的结果。最近，Heidi McBride和她的合作者在他们发现的线粒体衍生囊泡（MDV）中发现了线粒体和过氧化物酶体之间的新联系，这些囊泡似乎与哺乳动物细胞中预先存在的一部分过氧化物酶体融合。我们讨论了这种囊泡人口的背景下的代谢产物和/或大分子之间的交换途径，这些隔间的潜在作用。
Inter-organellar communication and interactions are necessary and accepted consequences of the segregation of biochemical functions into subcellular organelles. Recently, Heidi McBride and her collaborators found a novel link between mitochondria and peroxisomes in their discovery of mitochondria-derived vesicles (MDVs), which appear to fuse with a fraction of pre-existing peroxisomes in mammalian cells. We discuss the potential role of this vesicle population in the context of pathways for the exchange of metabolites and/or macromolecules between these compartments.