Preparation and characterization of fluorinated porcine hydroxyapatite
Preparation and characterization of fluorinated porcine hydroxyapatite
复制标题
氟化猪羟基磷灰石的制备及表征
DOI：
10.4012/dmj.2012-052
复制
发表时间：
2012-09-01
影响因子：
2.5
通讯作者：
Chen, Zhuofan
中科院分区：
文献类型：
--
作者：
Liu, Quan;Chen, Zetao;Chen, Zhuofan
采用简单的化学和热处理方法制备了含氟羟基磷灰石（FPHA）。利用扫描电子显微镜观察了FPHA的形态。采用XRD、EDX、FTIR和XPS等方法对氟的晶相、化学组成、官能团和结合能等理化特性进行了研究。使用氟离子浓度计检测从FPHA在HCl溶液（pH 3.0-4.0）中释放的游离氟离子的浓度。SEM、XPS、XRD和FTIR结果证实了猪羟基磷灰石（PHA）的结晶性。PHA和FPHA的晶体形态存在明显差异。FPHA释放的游离氟离子浓度随浸泡液浓度的增加和浸泡时间的延长而增加。本研究通过化学和热处理将氟化物成功地掺入PHA中。氟掺入PHA的速率是浸泡液中氟浓度的强函数。
Simple chemical and thermal treatments were applied to prepare fluorinated porcine hydroxyapatite (FPHA). Morphology of FPHA was observed using SEM. Physiochemical characteristics, namely crystalline phase, chemical composition, functional groups, and binding energy of fluorine were investigated using XRD, EDX, FTIR, and XPS respectively. Concentration of free fluoride ion released from FPHA in HCl solution (pH 3.0-4.0) was detected using a fluoride ion concentration meter. SEM, XPS, XRD, and FTIR results confirmed the fluorination of porcine hydroxyapatite (PHA). Significant crystal morphological difference was observed between PHA and FPHA. Concentration of free fluoride ion released from FPHA increased with rising concentration of immersion solution and length of immersion period. Fluoride was successfully incorporated into PHA by chemical and thermal processes in this study. Fluoride incorporation rate into PHA was a strong function of the fluorine concentration in the immersion solution.