Genetic linkage and bipolar affective disorder: progress and pitfalls.
Genetic linkage and bipolar affective disorder: progress and pitfalls.
复制标题
遗传连锁和双相情感障碍：进展和陷阱。
DOI：
10.1038/sj.mp.4000211
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发表时间：
1997
期刊：
影响因子：
--
通讯作者：
Baron,M
中科院分区：
文献类型：
--
作者：
Baron,M
The history of linkage studies in bipolar affective disorder is a convoluted affair punctuated by upswings and setbacks, hope and skepticism. Advances in genomics and statistical techniques, and the availability of well-characterized clinical samples, have bolstered the search for disease genes, leading to a new crop of findings. Indeed, recent reports of putative loci on chromosomes 18, 21, X, 4, 6, 13 and 15 have rekindled a sense of optimism. The new findings are reviewed and scrutinized, with implications for future research.
